Antivirals on the NCLEX
Acyclovir, oseltamivir, common antivirals: indications and side effects.
Antiviral classes for NCLEX: anti-herpes, anti-influenza, anti-HIV (covered separately), anti-hepatitis.
Anti-herpes
Acyclovir, valacyclovir, famciclovir. HSV, VZV, shingles. Nephrotoxicity (hydrate). Crystal nephropathy.
Anti-influenza
Oseltamivir (Tamiflu), zanamivir (inhaled), baloxavir. Effective if started within 48h of symptom onset. Reduce duration by 1-2 days.
Anti-RSV
Ribavirin (rarely used now). Palivizumab (Synagis, monoclonal, RSV prophylaxis in high-risk infants).
Frequently asked
When start oseltamivir?
Within 48h of flu symptom onset for maximum benefit. Still indicated later in severe cases.
Acyclovir IV, caution?
Crystal nephropathy. Hydrate well. Slow infusion.
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