Digoxin Level on the NCLEX
Therapeutic range, toxicity, antidote.
Digoxin level guides dosing in HF and AFib.
Therapeutic
0.5-2.0 ng/mL. Some experts target lower (<1.0) in HF.
Toxicity factors
Hypokalemia, hypomagnesemia, hypercalcemia, renal failure, drug interactions (amiodarone, verapamil).
Toxicity signs
GI (N/V, anorexia), visual (yellow-green halos), neuro (confusion), cardiac (arrhythmias).
Antidote
DigiFab (digoxin immune Fab) for severe toxicity.
Frequently asked
Hypokalemia and dig toxicity?
Low K+ amplifies dig effect → toxicity. Replace K+ when checking dig in diuretic patients.
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