Viral Hepatitis: NCLEX Priorities
Hep A, B, C, D, E: transmission, vaccination, treatment.
Five viral hepatitides. NCLEX tests transmission routes, vaccines, and B/C treatment.
Hep A
Fecal-oral. Self-limited. Vaccine available. Travel to endemic areas.
Hep B
Blood/sexual/perinatal. Chronic carriers risk cirrhosis, HCC. Vaccine routine at birth. Treatment: tenofovir, entecavir if active disease.
Hep C
Blood (IV drug use, pre-1992 transfusion). Often chronic. Direct-acting antivirals (DAAs), 95%+ cure rate with 8-12 weeks of therapy (sofosbuvir-based regimens).
Hep D
Requires Hep B coinfection. Worse outcomes.
Hep E
Fecal-oral. Severe in pregnancy. Self-limited in immunocompetent.
Post-exposure
Hep B: HBIG + vaccine for non-immune. Hep C: monitor, no PEP available.
Frequently asked
Hep B serology, what to know?
HBsAg = active infection. Anti-HBs = immunity. Anti-HBc IgM = acute. Anti-HBc IgG = past exposure.
Hep C cure rate today?
95%+ with current DAAs. Game-changing improvement.
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