Lithium Level on the NCLEX

Therapeutic range, toxicity, timing of draw.

Lithium has a narrow therapeutic window. Level guides dosing.

Therapeutic

0.6-1.2 mEq/L maintenance. 0.8-1.2 acute mania. >1.5 toxic.

When draw

12 hours after last dose. Steady state after 5-7 days on a dose.

Toxicity

Tremor (coarse), GI symptoms, confusion, ataxia. Severe: seizures, coma, death.

Acute toxicity treatment

Hold lithium. Hydrate. Dialysis if severe.

Frequently asked

Mild tremor at therapeutic level?

Common. Fine hand tremor expected. Coarse tremor = toxicity.

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