Vancomycin Trough Levels on the NCLEX
When to draw, target ranges, dose adjustment, nephrotoxicity.
Vancomycin trough monitors efficacy and toxicity. NCLEX tests timing and target.
When to draw
30 minutes before 4th or 5th dose (steady state).
Target
15-20 mcg/mL for serious infections (MRSA bacteremia, endocarditis, pneumonia, meningitis). 10-15 for skin/soft tissue.
High trough
Nephrotoxicity risk. Hold next dose. Reduce dose or extend interval. Recheck before resume.
Frequently asked
AUC-based dosing?
Newer approach. Better efficacy/toxicity balance. Many institutions transitioning.
Quick check
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